Endocrine Abstracts

Diabetes mellitus (DM) is one of the most serious comorbidities in kidney transplant recipients. New onset diabetes after kidney transplantation (NODAT) is a common and an important complication following solid organ transplantation. It is associated with poor graft function and increased cardiovascular complications. Therefore, management of hyperglycemia after transplantation is important to reduce diabetes-related risks. We aimed to compare the effects of pre-existing DM an...

Bone mineral disorders usually resolve after successful kidney transplantation. Serum calcium (Ca), phosphorus (P) and parathyroid hormone (PTH) levels tend to normalize within time. Serum Ca levels >10.2 mg/dL and PTH levels >150 pg/mL at 6th−12th months of transplantation is defined as persistent hypercalcemia and persistent hyperparathyroidism (PHPT) in recipients with normal graft function. Reported persistent hypercalcemia prevalence varies in wide range bet...

Metformin is considered to be the first choice in the treatment of type 2 diabetes mellitus. Lactic acidosis is a rare life-threatening complication of metformin with approximately 50% overall mortality. Metformin is contraindicated in patients with factors predisposing to lactic acidosis such as impaired renal function (eGFR <30 mL/min). Herein, we present a hemodialysis patient who developed lactic acidosis after inadvertent usage of metformin.Case...

Kidney disease occurs in diabetic patients during disease course in time. Diabetes duration, co-morbid diseases, presence of retinopathy, family history of diabetic nephropathy (DN) predict kidney involvement. Although DN is the initial diagnosis in diabetics with proteinuria, other diseases like primary glomerulonephritis (GN) could be the reason of kidney involvement. DN is increasing in proportion with the increase in diabetes prevalence, and it has been predicted to contin...

Native arteriovenous fistula (AVF) represents the best vascular approach for chronic hemodialysis. It is difficult to create an AVF in diabetic hemodialysis patients due to atherosclerotic changes in the arteries. Although AVF becomes useless after a successful kidney transplant, there is no accepted policy for preserving or ligating AVF. The aim of this study was to compare the fate of AVFs in diabetic and non-diabetic patients after kidney transplantation.<p class="abste...

The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is a disorder of impaired water excretion caused by inability to suppress secretion of antidiuretic hormone. The therapy of SIADH varies with severity of hyponatremia and presence or absence of symptoms. Non-peptide vasopressin receptor antagonists (vaptans) are effective at increasing sodium in euvolemic and hypervolemic states and appear safe. We aimed to evaluate the efficacy of tolvaptan in euvolemic h...

Tuberculosis (TB) infection incidence is still high among solid organ transplant recipients. TB in recipients can manifest several years after transplantation, especially in developing countries. Atypical clinical presentations and extrapulmonary involvement are not uncommon in recipients. Herein, we reported a kidney transplant recipient with TB abscess who admitted with fever and swelling on thyroid gland region.Case: A 57-year old female recipient und...

The efficacy of peritoneal dialysis (PD) is closely related to the status of the peritoneum. Long-term PD leads to structural and functional changes in the peritoneum and affects dialysis adequacy. Also high-glucose content of dialysate accelerates peritoneal fibrosis. It is reported that ultrasonography (USG) reflects parietal peritoneal membrane thickness and PD duration is related with peritoneal thickness. This study aimed to evaluate peritoneal thickness with USG in PD pa...